Organosulfur compounds and possible mechanism of garlic in cancer
نویسندگان
چکیده
منابع مشابه
Drug Metabolism and Pharmacokinetics of Organosulfur Compounds from Garlic
The medicinal activities of garlic organosulfur compounds identified include antitumor, antimicrobial, antifungal, antivirus, anti-atherosclerosis, blood lipids and sugar lowering, antithrombotic, anti-hypotension and immune modulation effects. These multi-targeted new agents may be especially promising since recently developed highly specific anti-cancer agents as well as other disease treatme...
متن کاملThe Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention
Garlic (Allium sativum) has been used for centuries as a prophylactic and therapeutic medicinal agent. Importantly, garlic has been suggested to have both cancer-preventive potential as well as significant enhancing effects on the immune system. While these observations are supported experimentally both in vitro and in vivo, the impact of garlic in assisting the immune system in the prevention ...
متن کاملOrganosulfur compounds from garlic (Allium sativum) oxidizing canine erythrocytes.
The sulfurous acid ester, trans-sulfurous acid allyl ester 3-allylsulfanyl-allyl ester 8, along with two known thiosulfinates was isolated from the aqueous ethanol extract of garlic (Allium sativum). The chemical structure of 8 was determined on the basis of spectroscopic data including high resolution mass and two-dimensional NMR techniques. All of these compounds induced methemoglobin formati...
متن کاملEvaluating the anti-neuroinflammatory capacity of raw and steamed garlic as well as five organosulfur compounds.
The anti-neuroinflammatory capacities of raw and steamed garlic extracts as well as five organosulfur compounds (OSCs) were examined in lipopolysaccharide (LPS)-stimulated BV2 microglia. According to those results, steaming pretreatment blocked the formation of alliinase-catalyzed OSCs such as allicin and diallyl trisulfide (DATS) in crushed garlic. Raw garlic, but not steamed garlic, dose-depe...
متن کاملCholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies.
The medicinal use of garlic dates back thousands of years, but there was little scientific support of its therapeutic and pharmacologic properties until recently. In the past decade, the cancer-protective effects of garlic have been well established by epidemiologic studies and animal experiments. However, the cardiovascular-protective properties of garlic are less well understood. In particula...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2010
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2009.12.007